"AC Immune and Lilly’s partnership will combine AC Immune’s proprietary Morphomer platform technology with Lilly’s commercial and clinical development capabilities. The collaboration with focus on AC’s lead molecule ACI-3024, which demonstrated tau aggregation inhibition in preclinical models."
Posts tagged as “AD”
"The Alzheimer's Drug Discovery Foundation's (ADDF) Diagnostics Accelerator initiative has announced a new $5 million commitment to projects targeting the development of biomarkers for frontotemporal degeneration (FTD), the most common dementia for people under 60. A new $2.5 million research investment from The Association for Frontotemporal Degeneration (AFTD) is being matched by a $2.5 million allocation of the ADDF's Diagnostics Accelerator funds."
"BioXcel Therapeutics Inc. ( BTAI ) announced proof-of-concept data from its Phase 1 study of IV (intravenous) dexmedetomidine or Dex for acute treatment of agitation in patients with Senile Dementia of the Alzheimer's Type or SDAT"
"Through a combination of assessments, screeners, workflows and clinical decision support algorithms, BrainCheck Care enables physicians to provide a detailed, personalized care plan to the patient and caregiver at the point of care."
"Since releasing initial BAN2401 results in July, excitement among investors has waned as detailed analysis has shown confounding results. However, many investors still see promise in the drug."
"The circadian clock—the body's molecular timekeeper—is best known for tuning our sleep, metabolism, digestion, and body temperature to the cycles of dark and light. Yet it controls other functions, as well. At the Society for Neuroscience meeting held November 3–7 in San Diego, researchers reported that activation of astrocytes and microglia in the brain is one of those. Disrupting the clock led to untimely inflammation that destroyed synapses. Researchers proposed that this phenomenon could exacerbate harm done by Alzheimer's pathology, and that correcting circadian imbalances might protect neurons in the face of neurodegeneration."
"Air pollution in Mexico City is associated with the development of Alzheimer disease in children and young adults and the evolving axonal damage can be identified using a novel Non-P-Tau assay for cerebrospinal fluid CSF: New study"
"We have reviewed decades of evidence from animal and human studies, across many different empirical methods, suggesting that when women begin taking hormone replacement therapy during menopause their risk of dementia and Alzheimer's in later years drops sharply, by 35 to 70 percent."
"Q-Tip, celebrated hip-hop artist, producer and founding member of A Tribe Called Quest took to Instagram recently to honor his mother, who is living with Alzheimer's . Known for lyrics that touch fans with their eloquence while simultaneously educating them on timely issues, the pioneering hip-hop star said that taking on the role of caregiver has been eye opening and inspirational."
"Developing Manager at the Alzheimer's Association, Colleen Hicks tells Robert Mangino about the signs of alzheimers and what people have to look for."