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Posts tagged as “AD”

GABA-A Receptor Structure Point to Drug Mechanisms | Alz Forum

"What do sedatives, general anesthetics, anti-anxiety drugs, alcohol, numerous recreational drugs, and allopregnanolone, a neurosteroid being tested in Alzheimer’s trials, have in common? They all tweak the activity of GABA-A receptors."

The Mathematical Fight Against Alzheimer’s Disease | Forbes


"In the U.S. alone, Alzheimer's disease is the sixth leading cause of death, according to the Alzheimer's Association's website, which also states "1 in 3 seniors dies with Alzheimer's or another dementia. It kills more than breast cancer and prostate cancer combined." Researchers are using many different approaches to tackle the disease. A surprising one? Mathematics."

Ask Ann Cannon: Losing my husband of 50 years was hard. So is the idea that now I’m somehow better off | The Salt Lake Tribune


"My husband of 50 years passed away shortly before Christmas this year. He’d had Alzheimer’s and naturally everyone — family and friends both — views his death as a blessing. They’re not wrong. Alzheimer’s is a terrible, terrible disease. I wouldn’t wish it on anybody. And, because I was my husband’s primary caregiver, the past few years have been unbelievably challenging."

Cognitive Decline Worsens With Memantine, ChEIs in Patients With Alzheimer’s | Neurology Advisor


"Investigators analyzed data from 10 clinical trials of patients with Alzheimer disease who received cholinesterase inhibitors or memantine.Patients with Alzheimer disease (AD) who receive cholinesterase inhibitors (ChEIs) or memantine in clinical trials experience greater cognitive decline than patients who receive neither medication, according to study results published in JAMA Network Open."