When Glial Clocks Fall Out of Sync, Inflammation Ensues | Alz Forum

“The circadian clock—the body’s molecular timekeeper—is best known for tuning our sleep, metabolism, digestion, and body temperature to the cycles of dark and light. Yet it controls other functions, as well. At the Society for Neuroscience meeting held November 3–7 in San Diego, researchers reported that activation of astrocytes and microglia in the brain is one of those. Disrupting the clock led to untimely inflammation that destroyed synapses. Researchers proposed that this phenomenon could exacerbate harm done by Alzheimer’s pathology, and that correcting circadian imbalances might protect neurons in the face of neurodegeneration.”
Read the full story at alzforum.org