New information on the pathological mechanisms of Alzheimer’s disease | Medical Xpress

“Immunoelectron microscopy image of accumulated tau protein on cell membrane. Researchers at the University of Helsinki have discovered a mechanism by which harmful tau protein aggregates are transmitted between neurons. Alongside amyloid plaques, tau aggregates in the brain are a significant factor in the progression of Alzheimer’s disease. Alzheimer’s disease is associated with two neuropathologies: amyloid plaques and tau aggregates, or tau protein accumulated in neurofibrillary tangles in neurons. Brain amyloid plaques are the better-known pathology, but the significance of tau to disease progression is equally important.”
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