New Definition of Alzheimer’s Hinges on Biology, Not Symptoms

A committee assembled by the National Institute on Aging and the Alzheimer’s Association published a new definition whereby Alzheimer’s disease equals the pathological accumulation of amyloid plaques and neurofibrillary tangles in the brain.They will be employed in studies to understand how Alzheimer’s develops, and to test treatments targeted to the aberrant biology.“This continues our movement toward thinking about Alzheimer’s disease as a neurobiological process rather than simply different clinical stages.Importantly, the framework aligns Alzheimer’s disease conceptually with the rest of medicine, said lead author Clifford Jack of the Mayo Clinic in Rochester, Minnesota.
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