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Association Between Psychosis and Development of Dementia in Older Men

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The authors recruited 37,770 men aged 65 to 85 from the Australian Electoral Roll between 1996 and 1998. During the 17.7-year study, dementia developed in 21.4% (n=8068), and 23,999 (63.5%) died during follow-up. Dementia developed approximately 3 times more frequently in people in whom a psychotic disorder was present. These disorders included schizophrenia, persistent delusional disorders, acute and transient psychotic disorders, schizoaffective disorders, and other non-organic or unspecified psychotic disorders.
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