Researchers led by Sylvia Villeneuve at McGill University in Montreal, Canada, suggest that the parental estimated year of onset (EYO) also has predictive value in late-onset Alzheimer’s disease. In the February 26 JAMA Neurology, they reported an association between higher amyloid burden and proximity to parental EYO in three separate cohorts of cognitively healthy older adults. Intriguingly, this relationship was seen only in women and ApoE4 carriers.
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Parental Age of Onset Helps Predict Amyloid Accumulation in Sporadic AD, Too
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