Continuous use of antiepileptic medications leads to an increased risk of Alzheimer’s disease and dementia, according to a recent study. The study, “ Use of Antiepileptic Drugs and Dementia Risk — an Analysis of Finnish Health Register and German Health Insurance Data ,” appeared in the Journal of American Geriatrics Society. Researchers compared the risk of dementia and antiepileptic medications both with and without known cognitive adverse effects. Specifically, using therapies that are known to impair cognitive function correlated with a 20% greater risk of Alzheimer’s and a 60% greater risk of dementia. The most frequently used medications with known cognitive effects include primidone, phenytoin, carbamazepine, clonazepam, and valproate.
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Antiepileptic Medications Raise Risk of Alzheimer’s, Dementia, Study Finds
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